Efficacy of Pyrethroid-Pyriproxyfen and Pyrethroid-Chlorfenapyr Long-Lasting Insecticidal Nets (LLINs) for the Control of Non- Anopheles Mosquitoes: Secondary Analysis from a Cluster Randomised Controlled Trial (cRCT).

The efficacy of a vector control tool in reducing mosquito biting is crucial for its acceptability. The present study compared the vector density of spp. And spp. across clusters, which received two dual-active ingredient (a.i.) long-lasting insecticidal nets (LLINs) and a standard pyrethroid-only LLIN, and assessed the seasonality of these mosquito genera. A total of 85,723 spp. and 144,025 spp. were caught over the study period. The density of and was reduced in all three arms over the study period. There was no evidence of a significant reduction in the indoor or outdoor density of spp. in either dual-a.i. LLIN arm as compared to the standard pyrethroid-only net arm. A similar trend was observed with spp. A high density of spp. was found both in rainy and dry seasons, while for spp., this was mainly observed during the rainy season. These results suggest that the novel insecticides in the dual-a.i. LLINs did not have an additional impact on these species and that pyrethroids might still be effective on them. Further work is required to determine whether these species of mosquitoes have resistance to the insecticides tested in this trial.