Pyrazolo[4,3-H]quinazolines as Cyclin-dependent Kinase Inhibitors for Treating Cancer

Current medicinal chemistry（2024）

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摘要

The application describes the synthesis of 1H-pyrazolo[4,3-H]quinazoline compounds for treating cell proliferation dysfunction and is a broad-spectrum and strongly-active inhibitor for a cell cyclin-dependent kinase (CDK).

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关键词

Pyrazolo-quinazoline,cyclin-dependent kinase,cancer,inflammation,cell-cycle regulation,cell proliferation

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