Arsenic trioxide-induced cytotoxicity in A549 cells: The role of necroptosis.

Maryam Jamil,Afshin Mohammadi-Bardbori,Omid Safa,Amin Reza Nikpoor,Azizollah Bakhtari, Mahnoosh Mokhtarinejad, Saghar Naybandi Zadeh,Amir Shadboorestan,Mahmoud Omidi

Drug research（2023）

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摘要

The A549 cells, after 48 h exposure to ATO at 50 and 100 μM, induces apoptosis and necroptosis. Due to the reduced expression of MLKL, it can be concluded that ATO is probably effective in the metastatic stage of cancer cells.

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关键词

cytotoxicity,a549 cells,trioxide-induced

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