Cluster analyses from the real-world NOVELTY study: six clusters across the asthma-COPD spectrum.

Rod Hughes,Eleni Rapsomaniki,Aruna T Bansal,Jørgen Vestbo,David Price,Alvar Agustí,Richard Beasley,Malin Fagerås,Marianna Alacqua,Alberto Papi,Hana Müllerová,Helen K Reddel

The journal of allergy and clinical immunology. In practice（2023）

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摘要

Cluster analyses in NOVELTY patients with asthma and/or COPD yielded identifiable clusters, with several discriminatory features that differed from conventional diagnostic characteristics. The overlap between clusters suggests that they do not reflect discrete underlying mechanisms, and points to the need for identification of molecular endotypes and potential treatment targets across asthma and/or COPD.

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clusters,spectrum,real-world,asthma-copd

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