Utilizing Mass Spectrometry to Detect and Isotype Monoclonal Proteins in Urine: Comparison to Electrophoretic Methods.

Danelle H Moonen,Mindy Kohlhagen,Surendra Dasari,Maria A Willrich,Taxiarchis Kourelis,Angela Dispenzieri,David L Murray

Clinical chemistry（2023）

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摘要

u-MASS-FIX is a reliable alternative to u-IFE with the added benefits of LC glycosylation detection and MP mass tracking between serum and urine. Furthermore, u-MASS-FIX is performed using neat urine. Eliminating the need to concentrate urine for u-IFE has potential to increase productivity by decreasing labor minutes per test.

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关键词

isotype monoclonal proteins,mass spectrometry,urine,electrophoretic methods

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