Pathogenic Gene Spectrum and Clinical Implication in Chinese Patients with Lupus Nephritis.

Changming Zhang, Xu Han, Ying Jin,Xiang Chen, Cheng Gong,Jiahui Peng,Yusha Wang, Xiaoxin Luo,Zhaohui Yang,Yangyang Zhang,Weiguo Wan,Xiaohui Liu,Jianhua Mao,Haiguo Yu,Jingyi Li,Li Liu,Li Sun,Sirui Yang,Yu An,Zhengzhao Liu,Erzhi Gao, Honghao Zhu,Yinghua Chen,Xiaomin Yu,Qing Zhou,Zhihong Liu

Clinical journal of the American Society of Nephrology : CJASN（2023）

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摘要

A small fraction of patients with lupus nephritis had identifiable pathogenic gene variants, primarily in NF-κB, type I interferon, PI3K/AKT, JAK/STAT, RAS/MAPK, and complement pathways.

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lupus nephritis, molecular genetics, outcomes

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