Non-invasive prenatal testing (NIPT) in twin pregnancies affected by early single fetal demise: A systematic review of NIPT and vanishing twins.

There is insufficient data to fully evaluate NIPT performance in pregnancies with a vanishing twin. However, existing studies suggest that NIPT can successfully detect common autosomal aneuploidies in pregnancies affected by a vanishing twin, but with a higher false positive rate. Further studies are needed to determine the optimal timing of NIPT in vanishing twin pregnancies. This article is protected by copyright. All rights reserved.