Towards precision dosing of aripiprazole in children and adolescents with autism spectrum disorder: linking blood levels to weight gain and effectiveness.

R A Hermans, S D T Sassen, S M Kloosterboer, C G Reichart, M E J Kouijzer,M M J de Kroon, D Bastiaansen, D van Altena,R H N van Schaik,K Nasserinejad, M H J Hillegers,B C P Koch, B Dierckx,B C M de Winter

British journal of clinical pharmacology（2023）

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摘要

Our results indicate a threshold with regard to safety, which suggests that therapeutic drug monitoring of aripiprazole could potentially increase safety in children and adolescents with ASD and behavioral problems.

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关键词

aripiprazole,blood levels,autism spectrum disorder,dosing

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