Unusual carriage of virulence genes sasX/sesI/shsA by nosocomial Staphylococcus haemolyticus from Brazil.

Ana C Silva-de-Jesus,Ciro C Rossi, Paula Ma Pereira-Ribeiro, Ana Lm Guaraldi,Marcia Giambiagi-deMarval

Future microbiology(2023)

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摘要
is an emerging threat in the nosocomial environment but only some virulence factors are known. The frequency of the gene (or orthologues ), encoding an invasiveness-related surface-associated protein, in was detected in different hospitals in Rio de Janeiro. 9.4% of strains were -positive, some were in the context of the ΦSPβ-like prophage and devoid of CRISPR systems, indicating potential transferability of their virulence genes. Gene sequencing evidenced that Brazilian harbored , instead of the usual , while had instead of , suggesting horizontal acquisition. The contexts of Brazilian favor transfer, which is alarming given the difficulty in treating infections caused by .
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关键词
coagulase negative staphylococci, horizontal gene transfer, sasX, sesI, virulence
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