Impact of prior alcohol use on the subsequent development of cancer cachexia in male and female mice.

Joseph A Laudato,Abigail L Tice, Bonde R Johnson, Allyson Russo,Michael L Rossetti,Blake O Bridges, Arthur Egan,Bradley S Gordon,Jennifer L Steiner

Alcoholism, clinical and experimental research（2023）

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摘要

Prior alcohol consumption accelerates or worsens the onset of certain aspects of cancer cachexia in a sex dependent manner, with males being more sensitive to these effects, even when abstinence from alcohol intake is achieved prior to tumor initiation.

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关键词

cancer cachexia, EtOH, skeletal muscle protein synthesis

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