Mena as a key enhancer factor of EMT to promote metastasis of human tongue squamous cell carcinoma.

Hao Cui,Xiang Liang,Yifei Zhu,Sadam Ahmed Elayah,Hong Qi,Linyang Xie,Zhichen Guo,Fang Siya,Yu Ming, Gong Yuxin,Junbo Tu,Sijia Na

Oral diseases（2023）

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摘要

Mena expression is associated with lymphatic metastasis and tumor stage and promotes TSCC invasion and metastasis by inducing the EMT process. Thus, Mena may be a biomarker for prognosis and targeted therapy in TSCC patients.

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关键词

epithelial-mesenchymal transition, Mena, metastasis, tongue squamous cell carcinoma

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