Systemic sclerosis: one year in review 2023.

Systemic sclerosis is a rare and chronic connective tissue disease resulting from an intricate pathogenesis and which is expressed in very heterogeneous clinical manifestations. Several studies try every year to unravel and shed a novel insight into the pathogenesis, organ involvement and treatment of this complex and severe disease. We herein provide an overview of the most relevant studies published in the literature in 2022.