Detection of subclinical epileptiform discharges in Alzheimer's disease using long-term outpatient EEG monitoring.

Neurobiology of disease(2023)

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摘要
Long-term ear-EEG monitoring detects epileptiform discharges in most patients with AD with a three-fold increased spike frequency compared to HC, which most likely originates from the temporal lobes. Since most patients showed epileptiform discharges with multiple recordings, elevated spike frequency should be considered a marker of hyperexcitability in AD.
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关键词
Subclinical epileptiform discharges,Alzheimer's disease,EEG,Long-term EEG,Ear-EEG,Wearable
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