Tracing back of relapse clones by Ig/TCR gene rearrangements reveals complex patterns of recurrence in pediatric acute lymphoblastic leukemia.

Ming-Zhu Jia,Wei-Jing Li,Chan-Juan Wang,Qing Zhang,Chao Gao,Xiao-Tong Huang,Ting Zhu,Rui-Dong Zhang,Lei Cui,Zhi-Gang Li

International journal of laboratory hematology（2023）

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摘要

Backtracking Ig/TCR gene rearrangements in relapse clones of pediatric ALL revealed complex patterns of clonal selection and evolution for leukemic relapse.

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关键词

acute lymphoblastic leukemia, clone evolution, clone selection, Ig/TCR gene rearrangements, relapse

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