Mechanism-Based Pharmacological Management of Chemotherapy-Induced Neuropathic Pain from Preclinical Studies to Clinical Prospective: Platinum-based drugs, Taxanes, and Vinca Alkaloids.

Nima Zafari,Mahla Velayati,Mina Maftooh,Majid Khazaei,Mohammadreza Nassiri,Seyed Mahdi Hassanian,Majid Ghayour-Mobarhan,Gordon A Ferns,Amir Avan

Current pharmaceutical design（2023）

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摘要

Taken together, due to the debilitating consequences of CIPN for the quality of life and clinical outcome of cancer survivors, future studies should focus on identifying underlying mechanisms contributing to CIPN as well as developing effective pharmacological interventions based on these mechanistic insights.

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关键词

Chemotherapy-induced peripheral neuropathy, neuropathic pain, platinum-based agents, taxanes, vinca alkaloids, chemotherapy

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