Prognostic Role of Circulating Tumor Cell Trajectories in Metastatic Colorectal Cancer.

Valentina Magri,Luca Marino,Chiara Nicolazzo,Angela Gradilone,Gianluigi De Renzi,Michela De Meo,Orietta Gandini, Arianna Sabatini,Daniele Santini,Enrico Cortesi,Paola Gazzaniga

Cells（2023）

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摘要

We confirmed the clinical value of CTC positivity, even with only one cell detected. CTC trajectories are better prognostic indicators than CTC enumeration at baseline. The reported prognostic groups might help to improve risk stratification, providing potential biomarkers to monitor first-line treatments.

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关键词

circulating tumor cells, circulating tumor cell trajectories, metastatic colorectal cancer, liquid biopsy, CellSearch((R)), precision medicine, prognostic and predictive biomarkers

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