A Metagenomic Analysis of the Virome of Inverted Papilloma and Squamous Cell Carcinoma.

Charles C L Tong,Xiang Lin,Tyler Seckar,Mateusz Koptyra,Michael A Kohanski,Noam A Cohen,David W Kennedy,Nithin D Adappa,Peter Papagiannopoulos,Edward C Kuan,Esther Baranov,Jalal B Jalaly,Michael D Feldman,Phillip B Storm,Adam C Resnick,James N Palmer,Zhi Wei,Erle S Robertson

International forum of allergy & rhinology（2023）

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摘要

There are over 200 HPV types that infect human epithelial cells, of which only a few are known to be high-risk. Our study demonstrated a trend of increasing prevalence of HPV18-E6 that correlated with histologic severity, which is novel and supports a potential role for HPV in the pathogenesis of IP. This article is protected by copyright. All rights reserved.

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human papillomavirus, inverted papilloma, malignancy, p16, sinonasal, squamous cell carcinoma

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