A novel Chr1-miR-200 driven whole transcriptome signature shapes tumor immune microenvironment and predicts relapse in early-stage lung adenocarcinoma.

Simon Garinet,Audrey Didelot,Laetitia Marisa,Guillaume Beinse,Marine Sroussi,Françoise Le Pimpec-Barthes,Elizabeth Fabre,Laure Gibault,Pierre Laurent-Puig,Sophie Mouillet-Richard,Antoine Legras,Hélène Blons

Journal of translational medicine（2023）

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摘要

This EMT and miR-200-related prognostic signature refines prognosis evaluation independently of tumor stage and paves the way towards assessing the predictive value of this LUAD clustering to optimize perioperative treatment.

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关键词

Resected lung adenocarcinoma, Prognostic biomarkers, miR-200 signature

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