Clinical relevance of cell-free DNA quantification and qualification during the first month after lung transplantation

Pascal Pedini,Benjamin Coiffard,Sylvia Casas,Audrey Boutonnet,Agnes Basire,Sophie Simon,Lucas Hubert,Coralie Frassati,Jacques Chiaroni,Martine Reynaud-Gaubert,Christophe Picard

Frontiers in immunology（2023）

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摘要

With the aim of considering cfDNA as a polyvalent non-invasive biomarker in transplantation, an algorithm combining the quantification of dd-cfDNA and small sizes of DNA may significantly classify the different types of allograft injuries.

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关键词

lung transplantation (LTx), graft rejection (MeSH), infections, chimerism, cell-free nucleic acids (cfNAs)

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