The estimated effect of season and vitamin D in the first trimester on pubertal timing in girls and boys: a cohort study and an instrumental variable analysis.

International journal of epidemiology(2023)

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摘要
Both first pregnancy trimester during November-April and lower 25(OH)D3 were associated with earlier pubertal timing in girls and boys.
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关键词
Seasonal effect, pregnancy season, vitamin D, 25-hydroxyvitamin D, prenatal exposure, delayed effects, maternal exposure, fetal programming, pubertal development, instrumental variable analysis
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