Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes.

Pavan K Bhatraju,David K Prince,Sherry Mansour,T Alp Ikizler,Edward D Siew,Vernon M Chinchilli,Amit X Garg,Alan S Go,James S Kaufman,Paul L Kimmel,Steve G Coca,Chirag R Parikh,Mark M Wurfel,Jonathan Himmelfarb

American journal of kidney diseases : the official journal of the National Kidney Foundation（2023）

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摘要

We identify 2 molecularly distinct AKI subphenotypes with differing risk of long-term outcomes, independent of the current criteria to risk stratify AKI. Future identification of AKI subphenotypes may facilitate linking therapies to underlying pathophysiology to prevent long-term sequalae after AKI.

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关键词

Acute kidney injury,long-term,major adverse kidney events,subphenotypes

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