Multiparametric quantitative MRI reveals progressive cortical damage over time in clinically stable relapsing-remitting MS.

Michelle Maiworm,Celona Hamid,Marlies Wagner,Ulrike Nöth,Ralf Deichmann,Alexander Seiler,René-Maxime Gracien

Journal of neurology, neurosurgery, and psychiatry（2023）

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摘要

Despite clinical stability, cortical T1, T2 and PD values increased over time, indicating progressive demyelination and increasing water content. These parameters represent promising surrogate parameters of diffuse cortical inflammation in RRMS.

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关键词

multiple sclerosis, MRI, neuroimmunology

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