Chrysin prevents inflammation-coinciding liver steatosis via AMPK signalling.

Chuanyue Gao, Huan Zhang,Lulin Nie,Kaiwu He,Peimao Li, Xingxing Wang,Zaijun Zhang,Yongmei Xie,Shupeng Li,Gongping Liu,Xinfeng Huang, Huiping Deng,Jianjun Liu,Xifei Yang

The Journal of pharmacy and pharmacology（2023）

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摘要

In summary, CN treatment reduced lipid metabolism by AMPK and inflammasome activation by NLRP3 inhibition, ultimately improving NAFLD progression. These findings suggest that CN could be a potential treatment candidate for the NFLAD condition.

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关键词

NAFLD, chrysin, inflammation, inflammasome, AMPK

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