AR-A014418 regulates intronic polyadenylation and transcription of PD-L1 through inhibiting CDK12 and CDK13 in tumor cells.

Ganggang Zhang,Bin Lan,Xin Zhang,Mengyao Lin,Yi Liu,Junsong Chen,Fang Guo

Journal for immunotherapy of cancer（2023）

引用 2|浏览2

暂无评分

摘要

Our work identifies a new regulatory pathway for PD-L1 expression and discovers CDK12 and CDK13 as promising drug targets for immune modulation and combined therapeutic strategies.

查看译文

关键词

Immunotherapy, B7-H1 Antigen

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要