Inhibited postprandial retrograde cyclic motor pattern in the distal colon of patients with diarrhea predominant irritable bowel syndrome.

Lukasz Wiklendt,Reizal Mohd Rosli,Raghu Kumar, Niranchan Paskaranandavadivel,Peter A Bampton,Lyn Maslen,Marcello Costa,Simon J Brookes,Gregory O'Grady,Phil G Dinning

American journal of physiology. Gastrointestinal and liver physiology（2023）

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摘要

IBS-D patients show reduced prevalence of the retrograde cyclic motor pattern post-prandially compared to the marked prevalence in healthy adults. We hypothesize that this reduction may allow premature rectal filling, leading to postprandial urgency and diarrhea.

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关键词

colon, irritable bowel syndrome, meal, motility

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