Corneal confocal microscopy reveals small nerve fibre loss correlating with motor function in adult spinal muscular atrophy.

Andreas Thimm,Svenja Brakemeier,Merve Dag, Juan Munoz Rosales,Benjamin Stolte,Christoph Kleinschnitz,Mark Stettner,Tim Hagenacker

European journal of neurology（2023）

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摘要

CCM reveals sensory neurodegeneration in SMA, thereby supporting a multi-system view of the disorder. Subclinical small nerve fibre damage correlated with motor function. Thus, CCM may be ideally suited for treatment monitoring and prognosis.

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spinal muscular atrophy,small nerve fibre loss,corneal confocal microscopy,motor function

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