18F-FMISO PET-guided dose escalation with multifield optimization intensity-modulated proton therapy in nasopharyngeal carcinoma.

Kiattisa Sommat,Aaron Kian Ti Tong,Ashley Li Kuan Ong,Jing Hu,Sze Yarn Sin,Winnie Wing Chuen Lam,Wanying Xie,Yiu Ming Khor,Cindy Lim,Tze Wei Lim,Sathiyamoorthy Selvarajan,Fuqiang Wang,Terence Wee Kiat Tan,Joseph Tien Seng Wee,Yoke Lim Soong,Kam Weng Fong,Tiffany Hennedige,Thng Choon Hua

Asia-Pacific journal of clinical oncology（2023）

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摘要

The utility of boost to the hypoxic volume before standard course of radiotherapy with IMPT is dosimetrically feasible in selected patients. Clinical trials are warranted to determine the clinical outcomes of this approach.

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关键词

18F-FMISO PET, dose escalation, hypoxia, intensity-modulated proton therapy, nasopharyngeal cancer

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