Total neoadjuvant treatment to increase the clinical complete response rate for distal locally advanced rectal cancer (TESS): A study protocol of a prospective, open-label, multicenter, single-arm, phase 2 trial.

Shuang Liu,XiaoZhong Wang,YeZhong Zhuang,ShouMin Bai,XiaoJun Wu,YiJing Ye,HuiLong Luo,HaiNa Yu,QiaoXuan Wang,Hui Chang,ZhiFan Zeng,PeiQiang Cai,ZhiZhong Pan,YuanHong Gao,Gong Chen,WeiWei Xiao

Cancer medicine（2023）

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摘要

The TESS trial aims to explore a new TNT strategy, which is expected to increase the rate of cCR and sphincter preservation rate. This study will provide new options and evidence for a new sandwich TNT strategy in patients with distal LARC.

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关键词

clinical trials, neoadjuvant chemotherapy, rectal cancer, surgical oncology

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