Resveratrol inhibits restenosis through suppressing proliferation, migration and trans-differentiation of vascular adventitia fibroblasts via activating SIRT1.

Mengyun Li,Lan Luo, Ying Xiong,Fuyu Wang,Yun Xia,Zongze Zhang,Jianjuan Ke

Current medicinal chemistry（2023）

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摘要

Above results indicated RSV inhibited restenosis after balloon angioplasty through suppressing proliferation, migration and trans-differentiation of VAFs via regulating SIRT1- TGF-β1-SMAD3-NOX4 to decrease ROS.

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关键词

vascular adventitia,sirt1,trans-differentiation

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