An Eosinophil Peroxidase Activity Assay Accurately Predicts Eosinophilic Chronic Rhinosinusitis.

Kristine A Smith,Amarbir S Gill,Chelsea E Pollard,Jorgen S Sumsion,Hedieh Saffari,Shaelene Ashby,Benjamin L Witt,Paige A Shipman,David A Gabrielsen,Michael T Yim,Joshua M Levy,Gretchen M Oakley,Richard R Orlandi,Gerald J Gleich,Jeremiah A Alt,Abigail Pulsipher

The Journal of allergy and clinical immunology（2023）

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摘要

This investigation evaluates a nasal swab sampling method and EPX activity assay that accurately confirms eCRS. This method could potentially address the unmet need to identify sinonasal tissue eosinophilia at the point-of-care, as well as to longitudinally monitor eosinophil activity and treatment response.

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关键词

eosinophil peroxidase activity,chronic rhinosinusitis,eosinophilic

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