Association between HLA class II Polymorphism and Knee Osteoarthritis in a Thai Population.

Clinical laboratory(2023)

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摘要
Knee OA was more pronounced among females than males, especially those aged  60 years. In addition, a contrary effect was found regarding HLA-DQB1*03 (DQ9) and HLA-DRB1*14, in whom the presence of HLA-DQB1*03 (DQ9) seems to promote disease susceptibility, whereas HLA-DRB1*14 appears to be a protective factor against knee OA. However, further study with a larger sample size is suggested.
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关键词
human leukocyte antigen (HLA), alleles, osteoarthritis (OA), Thais
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