Prevalence and prognostic value of prodromal symptoms in relapsing-remitting multiple sclerosis.

Karolina Kania,Wojciech Ambrosius,Klara Dyczkowska,Wojciech Kozubski,Alicja Kalinowska-Lyszczarz

Neurologia i neurochirurgia polska（2023）

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摘要

Prodromal pain, urinary and cognitive complaints (especially when these lead to deterioration of everyday functioning) were associated with a higher EDSS increase rate, and may thus be regarded as possible predictors of worse clinical outcomes in RRMS patients.

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multiple sclerosis, prodromes, disease predictors, RIS, preclinical phase

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