An Hspa8 variant is a shocking modifier of spinal muscular atrophy in mice.

Anton James Blatnik,Arthur Harry Macleod Burghes

Neuron（2023）

引用 0|浏览5

暂无评分

摘要

In this issue of Neuron, Kim et al. show that an Hspa8 variant modifies disease phenotypes in a mouse model of spinal muscular atrophy. Hspa8 facilitates the correct folding of proteins, enhances SNARE assembly, and influences SMN2 splicing.

查看译文

关键词

spinal muscular atrophy,hspa8 variant,mice

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要