Super Enhancer-Associated Circular RNA-CircKrt4 Regulates Hypoxic Pulmonary Artery Endothelial Cell Dysfunction in Mice.

Cui Ma,Xiaoying Wang,Lixin Zhang,Xiangrui Zhu,June Bai,Siyu He,Jian Mei,Jiaqi Jiang,Xiaoyu Guan,Xiaodong Zheng,Lihui Qu,Daling Zhu

Arteriosclerosis, thrombosis, and vascular biology（2023）

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摘要

These findings demonstrate that a super enhancer-associated circular RNA-circKrt4 modulates PAEC injury to promote pulmonary hypertension by targeting Pura and Glpk.

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关键词

pulmonary artery,enhancer-associated,rna-circkrt

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