Primary Aldosteronism: Spatial Multiomics Mapping of Genotype-Dependent Heterogeneity and Tumor Expansion of Aldosterone-Producing Adenomas.

Siyuan Gong,Na Sun,Lucie S Meyer,Martina Tetti,Christina Koupourtidou, Stefan Krebs,Giacomo Masserdotti,Helmut Blum,William E Rainey,Martin Reincke,Axel Walch,Tracy Ann Williams

Hypertension (Dallas, Tex. : 1979)（2023）

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摘要

Our findings provide insight into intra- and intertumoral transcriptional heterogeneity and support a role for prooxidant versus antioxidant systems in APA pathogenesis highlighting genotype-dependent capacities for tumor expansion.

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关键词

spatial multiomics mapping,tumor expansion,genotype-dependent,aldosterone-producing

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