Overexpression of lncRNA-MEG3 inhibits endometrial cell proliferation and invasion via miR-21–5p/DNMT3B/Twist

Shaoyan Yang,Limei Feng, Qin Zhang,Lu Wu,Qinghua Zhao,Youfang Hou, Bo Yan,Suxian Zhang

Clinics（2023）

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摘要

•MEG3 expressed exceptionally low in the ectopic endometrial.•Overexpression of MEG3 inhibits hESCs proliferation and invasion.•MEG3 is a ceRNA that has regulatory effects on miR-21–5p/DNMT3B axis.•DNMT3B inhibits Twist expression after upregulation of MEG3 action.

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关键词

endometrial cell proliferation,mir-21–5p/dnmt3b/twist,cell proliferation,lncrna-meg

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