Spatial transcriptomics of murine bone marrow megakaryocytes at single-cell resolution

Julia Tilburg,Andrew P. Stone,James M. Billingsley,David K. Scoville,Anna Pavenko,Yan Liang,Joseph E. Italiano,Kellie R. Machlus

Research and Practice in Thrombosis and Haemostasis（2023）

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摘要

•Platelet-producing cells in the bone marrow are composed of a varied population.•New technology can reveal gene expression variation of intact tissues at a single-cell level.•Gene expression was quantified from single cells with some variation related to cell location.•Improvements in this technology will help map variation in platelet-producing cells in the marrow.

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关键词

spatial transcriptomics,murine bone marrow,bone marrow,single-cell

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