Locus coeruleus and substantia nigra neuromelanin magnetic resonance imaging differentiates Parkinson’s disease and essential tremor

Xinhui Wang,Pei Huang,Ewart Mark Haacke,Yu Liu,Youmin Zhang,Zhijia Jin,Yan Li,Qiuyun Xu, Peng Liu,Shengdi Chen,Naying He,Fuhua Yan

NeuroImage: Clinical（2023）

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摘要

•Use changes of substantia nigra and locus coeruleus for differential diagnosis.•The neuromelanin CNR of the locus coeruleus is different in two tremor diseases.•The AUC of the combined diagnostic model can reach 0.92.

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PDTD,ET,SN,LC,NM-MRI,NMV-SN-R,NMV-SN-L,NMA-LC-R,NMA-LC-L,NMCNR-SN-R,NMCNR-SN-L,NMCNR-LC-R,NMCNR-LC-L

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