Posterior fossa ependymoma in children: A long-term single-center experience

•Complete surgical removal of posterior fossa ependymoma still is the most important prognostic factor for survival.•Second-look surgery must be done in case of incomplete removal.•Aggressive surgery is associated with a higher rate of postoperative sequelae but is justified to improve the patient's survival.•Clinical trials with new-targeted therapy are essential to improve the prognosis.