(Bio)electroanalysis of microtubule-targeting agents used in cancer chemotherapy

Dana Elena Popa,Iulia Gabriela David,Mihaela Carmen Cheregi,Emilia Elena Iorgulescu,Mihaela Buleandră

Microchemical Journal（2023）

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摘要

•Holistic review on electrochemistry of microtubule-targeting agents (MTAs) used in chemotherapy.•MTAs electrochemical behavior on bare and modified electrodes.•Comparison of the MTAs electroanalytical methods performance parameters.•Investigation of the interaction of MTAs with significant biomolecules and cancer cells.•Drawbacks and perspectives in development of reliable MTAs electrochemical sensors.

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关键词

Microtubule-targeting agents,Chemotherapy,(Bio)electroanalysis,Pharmaceutical formulations,Biological samples,Drug-DNA interactions

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