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Renal Function Underpins the Cyclooxygenase-2: Asymmetric Dimethylarginine Axis in Mouse and Man

Plinio Ferreira,Ricky Vaja, Maria Lopes-Pires,Marilena Crescente,He Yu,Rolf Nüsing,Bin Liu,Yingbi Zhou,Magdi Yaqoob,Anran Zhang,Matthew Rickman,Hilary Longhurst,William E. White,Rebecca B. Knowles,Melissa V. Chan,Timothy D. Warner,Elizabeth Want,Nicholas S. Kirkby,Jane A. Mitchell

Kidney International Reports（2023）

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摘要
In human and mouse models, where renal function is compromised because of loss of COX-2/PGI signaling, ADMA levels are increased.
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关键词
ADMA,kidney,nitric oxide,NSAID,prostacyclin
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