Prediction of adenomyosis diagnosis based on MRI

•We present the first clinical diagnostic tool combining both MRI and clinical parameters to predict histopathology adenomyosis diagnosis on an individual level with good accuracy.•Our model would be especially useful in cases of mild or atypical adenomyosis where MRI is indicated.•External validation is needed in other (prospective) settings, where clinicians can apply our results to aid in patient counselling.