Computational Engineering of Previously Crystallized Pyruvate Formate-Lyase Activating Enzyme Reveals Insights into SAM Binding and Reductive Cleavage.
JOURNAL OF BIOLOGICAL CHEMISTRY(2023)
Key words
crystallization,iron–sulfur cluster,iron–sulfur enzyme,protein redesign,radical SAM,reductive SAM cleavage,S-adenosylmethionine
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