Evidence for a causal association between psoriasis and psychiatric disorders using a bidirectional Mendelian randomization analysis in up to 902,341 individuals.

Yujie Wang,Xinquan Wang,Xiaoyu Gu, Jie Pan,Zhen Ouyang,Wenrui Lin,Wu Zhu,Mi Wang,Juan Su

Journal of affective disorders（2023）

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摘要

This study has supported the causal association of psoriasis with MDD and bipolar disorder, and the subtype PsA with bipolar disorder, which informed the intervention for mental illnesses in patients with psoriasis.

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关键词

Psoriasis,Major depressive disorder,Bipolar disorder,Schizophrenia,Anxiety disorders,Mendelian randomization

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