Effect of bromelain on periodontal destruction and alveolar bone in rats with experimental periodontitis

International Immunopharmacology(2023)

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摘要
•Bromelain decreased the bone loss in Micro-BT analysis.•Bromelain inhibited periodontal and alveolar tissue destruction.•TNF-α, IL-6, and M-CSF levels decreased with Bromelain in experimental periodontitis models.•MMP-8 and RANKL values were decreased and OPG was increased by Bromelain.•Bromelain regulated oxidative stress by decreasing MDA and increasing GPx, and SOD.
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关键词
Alveolar bone loss,Antioxidant,Bromelain,Periodontal diseases,Rats
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