Green synthesis of ZnO-Ag nanocomposite using Stenotaphrum secundatum grass extract: Antibacterial activity and anticancer effect in oral squamous cell carcinoma CAL 27 cells

Parameshwar Jakinala,Harikrishna Naik Lavudi,Neelima Angali, Santhosh Ganderla,Krishna K. Inampudi,Sai Balaji Andugulapati,M. Srinivas,Madhumohan Rao Katika

Inorganic Chemistry Communications（2023）

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摘要

•Stenotaphrum secundatum (buffalo grass) grass extract used for the formation of novel ZnO-Ag nanocomposites (NCs) using green chemistry.•Phytochemical components responsible for the bio-reduction of ZnO-Ag NCs were identified with GC–MS.•Structural and functional characterization of the nanoparticles were determined.•Biosynthesized ZnO-Ag NCs showed enhanced antibacterial and anticancer activity compared to ZnONPs and AgNPs.•ZnO-Ag NCs significantly inhibited cell cycle and induces apoptosis.

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关键词

Stenotaphrum secundatum, Silver nanoparticles, Zinc nanoparticles, ZnO-Ag nanocomposite, Antimicrobial, Anticancer

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