Targeting plasma cells in systemic autoimmune rheumatic diseases – Promises and pitfalls

Tobit D. Steinmetz,Gwenny M. Verstappen,Jolien Suurmond,Frans G.M. Kroese

Immunology Letters（2023）

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摘要

•Plasma cells differ according to their origin, maturity, and among diseases.•Plasma cell alterations are common in systemic autoimmune rheumatic diseases.•Depletion of plasma cells is a promising new treatment approach.•Targeting plasma cells can be disease-specific and precise.

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关键词

Antibody-secreting cells,Plasma cells,Plasmablasts,Autoimmune rheumatic diseases,Treatment

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