Lb-456088-1 left bundle branch area pacing compared to biventricular pacing for cardiac resynchronization therapy: results from international lbbap collaborative study group

Cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is well-established therapy in patients with reduced left ventricular ejection fraction (LVEF), heart failure and wide QRS or indication for pacing. BVP achieves CRT through non-physiological fusion of paced wave-fronts from the RV endocardium and LV epicardium. Conduction system pacing utilizing left bundle branch area pacing has recently shown to be a safe and a more physiologic alternative to BVP. The aim of this study was to compare the clinical outcomes between BVP and LBBAP among patients undergoing CRT.