The most efficient and effective BRCA1/2 testing strategy in epithelial ovarian cancer: Tumor-First or Germline-First?
Gynecologic Oncology(2023)
摘要
•An efficient strategy for genetic testing in epithelial ovarian cancer is highly desired.•We compared costs and effects of two strategies: Tumor-First and Germline-First.•Average testing costs per patient are much lower with the Tumor-First strategy.•In a likely scenario, more patients and relatives with a germline BRCA1/2 PV are identified with the Tumor-First strategy.
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关键词
Ovarian cancer,BRCA,Heredity,Cost analysis,Genetic testing
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