Improving genetic testing following abnormal mismatch repair immunohistochemistry results in endometrial cancer
Gynecologic Oncology(2023)
摘要
•In endometrial cancer (EC) cases with abnormal immunohistochemistry, a protocol aimed to increase germline testing (GT).•In eligible patients, genetic counseling referrals (GCRs) but not GT significantly increased after the protocol.•About 15% of eligible patients still did not undergo GT following the protocol implementation.•Further measures, such as universal GT in patients with EC, should be considered to appropriately screen for Lynch Syndrome.
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关键词
genetic testing,cancer
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